The endocannabinoid system is extremely complex it consists of numerous G protein coupled receptors (CB receptors are included in this class) transient receptor potential channels and nuclear receptors. This is just a glimpse at how your diet plays a huge role in your health. Cut out the crap replace it with goodness! Phytocompounds found in all plants and fungi feed this system!
Aside from Cannabis numerous phytocompounds have shown affinity to CB receptors.
“Different widespread (canonical) triterpenoids have already been shown to inhibit metabolic enzymes of the major EC 2‐AG, ubiquitous plant flavonoids were found to inhibit FAAH, the metabolic enzyme degrading AEA and other N‐acylethanolamines (NAEs) and to weakly modulate CB receptors. Intriguingly, the ubiquitous plant sesquiterpene β‐caryophyllene (BCP) has been shown to exert potent CB2 receptor‐mediated cannabimimetic effects in mice and N‐alkylamides from maca (Lepidium meyenii Walp.) and black pepper (Piper nigrum L.) show cannabimimetic effects in vitro and in vivo respectively. The polyacetylene falcarinol (carotatoxin) present in carrots and other vegetables was shown to inhibit CB1 receptor activation by AEA in vitro. Several isoprenylated analogues of the naturally occurring plant stilbenoid trans‐resveratrol bind to both CB1 and CB2 receptors with low affinity. The widespread dietary triterpnoids oleanolic acid (present in olive oil) and ursolic acid have been shown to inhibit ABDH12, an enzyme that controls 2‐AG levels in immune cells. Thus, different dietary phytochemicals have already been shown to directly or indirectly modulate the ECS”
Phytochemicals found in cinnamon, garlic, mustard, tumeric, horseradish, tobacco, mint, cannabis, cayenne pepper and oregano have been proven to react with transient receptor potential channels. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240255/
Phytochemicals found in ginseng, gingko biloba, cayenne pepper, sesame seeds, yin yang, grapes and oregano have shown affinity to nuclear receptors (PPARa and PPARy). https://www.sciencedirect.com/…/artic…/pii/S2211383517301624
Photo credit: https://profofpot.com/thc-cbd-cell-targets-receptors/